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quinupristin/dalfopristin will enhance the amount or effect of sparsentan by affecting hepatic/intestinal enzyme CYP3A4 metabolism.2 The 50 percent-lifetime of quinupristin and its metabolites is close to a few several hours, While the 50 percent-lifetime of dalfopristin and its metabolites is around just one hour.quinupristin/dalfopristin will red